Scientists at the Wellcome Trust – MRC Cambridge Stem Cell Institute are part of a team who have succeeded in growing miniature functional models of the lining of the womb (uterus) in culture. These organoids (lab-grown clusters of cells mimicking the womb lining) could provide new insights into the early stages of pregnancy and conditions such as endometriosis, a painful condition that affects as many as two million women in the UK.
Turco, MY et al. Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium. Nature Cell Biology; 10 April 2017; DOI: 10.1038/ncb3516