Earlier Publications

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Azim Surani Award

Reprogramming of DNA observed in human germ cells for first time

Some genes that escape reprogramming may contribute to human diseases in subsequent generations A team of researchers led by the University of Cambridge Read more >
Graph Abstract

Single cell technologies uncover molecular drivers of stem cell function

Novel technologies using single stem cells can now be used together to help define the molecules responsible for stem cell function, according to research Read more >
mouse cortex

The NuRD complex regulates neural cell fate determination and differentiation in the cerebral cortex

Chromatin modifying complexes have key roles in regulating various aspects of neural stem cell biology, including self-renewal and neurogenesis. Our data Read more >
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Link between proteins points to possibilities for future Alzheimer’s treatments

Researchers from Rick Livesey group have found that the proteins that control the progression of Alzheimer’s are linked in a pathway, and that drugs Read more >
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Activin/Nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions

Human embryonic stem cells are capable to self-renew while maintaining the capacity to differentiate into a broad diversity of cell types. Activin/Nodal Read more >
Epicardium

Robust derivation of epicardium from human pluripotent stem cells

The embryonic epicardium gives rise to key cardiovascular tissue including coronary artery smooth muscle cells and cardiac fibroblasts. We have modelled Read more >
Grey matter

The role of immune cells, glia and neurons in white and grey matter pathology in multiple sclerosis

This review aims at providing a comprehensive overview of the interplay between inflammation, glial/neuronal damage and regeneration throughout the course Read more >
Mini-lungs

Scientists grow ‘mini-lungs’ to aid the study of cystic fibrosis

SCI Researchers have successfully created ‘mini-lungs’ using stem cells derived from skin cells of patients with cystic fibrosis, and have Read more >
Figure

CDK6 levels regulate quiescence exit in human hematopoietic stem cells

Life-long production of blood cells is guaranteed by rare haematopoietic stem cells (HSC), which divide very infrequently and spend most of the time in Read more >
Figure 4

Activin/Nodal signalling in stem cells

Ludovic Vallier and Siim Pauklin publish areview in Development describing the function of Activin/Nodal/TGFbeta signalling in stem cells and diseases. Read more >

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