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Professor Christine Watson

128 Watson ChristineProfessor Christine Watson

Stem cell and lineage determining factors in mammary gland

Laboratory Location: Cambridge Cancer Centre 

Departmental Affiliation: Department of Pathology

 

Research

We are interested in identifying transcriptional regulators that control lineage commitment of mammary stem cells. We have identified a novel gene, Zfp157, that is a master regulator of the alveolar lineage. Further work is focussed on lineage tracing  using fluorescent fusion proteins and H2B-GFP to isolate and characterise long label-retaining cells.

Watson research 2017

The Running Rainbow: Depth coding confocal image of a branching mammary duct. Image credit: Bethan Lloyd-Lewis, Felicity Davis, Olivia Harris 

 

External links

www.path.cam.ac.uk/directory/christine-watson 

www.cambridgecancercentre.org.uk/users/cjwatson

 

CSCI collaborators

Doug Winton