Pina headshot

Dr Cristina Pina

Haematopoietic stem cells

Departmental Affiliation:

Department of Haematology


Haematopoietic stem cells balance molecular programmes of self-renewal and differentiation in order to sustain mature blood cell production and maintain a pool of undifferentiated multipotent cells throughout the lifetime of the individuals. Corruption of some of these programmes in favour of self-renewal and/or blocking differentiation may result in malignant transformation to generate leukaemia. Additionally, stem cells have the capacity to respond to increased demands in production of mature lineages, e.g. upon injury.

External links

SCI Collaborators

Brian Huntly

Alfonso Martinez-Arias

George Vassiliou

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