Joshua Bernstock - photo

Joshua Bernstock

2013 - 2016


PhD Programme/Sponsor: NIH OxCAm

Supervisor: Dr Stefano Pluchino

Co-Supervisor/Mentor: Professor Robin Franklin

Start year: 2013

Other: MD/PhD student

Key Publications

1) Bernstock JD, Lee YJ, Southall N, Johnson KR, Maric D, Volpe G, Kouznetsova J, Peruzzotti-Jametti L, Zheng W, Pluchino S, Hallenbeck JM. A Novel Quantitative High-throughput Screen Identifies Drugs that both Activate SUMO-conjugation via the Inhibition of MicroRNAs 182 and 183 and Facilitate Neuroprotection in a Model of Oxygen and Glucose Deprivation. J Cereb Blood Flow Metab. 2015 Oct 23. PMID: 26661196.

2) Zhao J, Mou Y, Bernstock JD, Klimanis D, Spatz M, Johnson K, Klinman DM, Xiaohong Li X, Hallenbeck JM. Synthetic oligodeoxynucleotides containing multiple telemeric TTAGGG motifs suppress inflammasome activity in macrophages subjected to oxygen and glucose deprivation and reduce ischemic brain injury in SHR-SP rats. PLOS ONE. 2015 Oct 16. PMID: 26473731.

3) Miyake S, Wakita H, Bernstock JD, Castri P, Ruetzler C, Miyake J, Lee YJ, Hallenbeck JM. Hypophosphorylation of Ribosomal Protein S6 is a Molecular Mechanism Underlying both Hibernation and Induced Ischemic Tolerance. J Neurochem. 2015 Dec. PMID:26375300.

4) Mallucci G, Peruzzotti-Jametti L, Bernstock JD, Pluchino S. The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis. Prog Neurobiol. 2015 Apr. PMID: 25802011.

5) Bernstock JD, Caples CM, Wagner SC, Kang DG, Lehman RA Jr. Characteristics of combat-related spine injuries: a review of recent literature. Mil Med. PMID: 25939103.

6) Lee YJ, Mou Y, Klimanis D, Bernstock JD, Hallenbeck JM. Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance. Front Cell Neurosci. PMID: 25538566.

7) Hermann DM, Peruzzotti-Jametti L, Schlechter J, Bernstock JD, Doeppner TR and Pluchino S. Neural precursor cells in the ischemic brain – integration, cellular crosstalk, and consequences for stroke recovery. Front Cell Neurosci. 2014 Sep 16. PMID: 25278840.

8) Budinich CS, Chen H, Lowe D, Rosenberger JG, Bernstock JD, McCabe JT. Mouse brain PSA-NCAM levels are altered by graded-controlled cortical impact injury. Neural Plast. PMID: 22848850.

9) Bernstock J Verheyen J, Huang B, Hallenbeck J and Pluchino S. Typical and Atypical Stem Cell Niches of the Adult Nervous System in Health and Inflammatory Brain and Spinal Cord DiseasesBook Chapter Published: August 1, 2014.

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