A Guinot

Anna Guinot

2010 - 2014

Studentship Details


Dates of Study: Oct 2010 - Sep 2014

PhD Supervisor: Dr Juan-Jose Ventura

Studentship Sponsor: Herchel Smith

Thesis Title: Human lung bronchioalveolar stem cells in homeostasis and cancer


Post PhD
Anna is currently working as a Postdoc with Ian Frew at The Institute of Physiology, University of Zurich, Switzerland.

Plain English

I have worked on understanding how lung stem cells renew and heal adult human lungs and how deviations of their tight control can lead to lung cancer.

Key Publications

  1. Oeztuerk-Winder F, Guinot A, Ochalek A and Ventura JJ. Regulation of human lung alveolar multipotent stem cells by a novel p38a MAPK/miR-17-92 axis. EMBO J. 2012.
  2. Guinot A, Oeztuerk-Winder F and Ventura JJ. MiR-17-92/p38a dysregulation enhances Wnt signal and selects Lgr6+ cancer stem cell-like cells during human lung adenocarcinoma progression. In preparation.
  3. Oeztuerk-Winder F, Lemke A, Fink J, Guinot A, Page M, Jensen K and Ventura JJ. Lrig1 marks a distinct population of early progenitors with potential to regenerate all bronchiolar cell types. Nature Cell Biology (in press).

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