2010 - 2014
Dates of Study: Oct 2010 - Sep 2014
PhD Supervisor: Dr Kim Jensen
Studentship Sponsor: The Medical Research Council
Thesis Title: Characterisation of Lrig1 expressing stem cells
In January 2015, Mahalia started a Research Associate at University College London (UCL), Institute for Child Health, London.
Legend: This image show the locations of different stem cell populations in the hair follicle.
Normal skin contains several different types of stem cells in distinct regions of the epidermis. We found each of these types of stem cells only looks after its local region as a self-contained compartment of the skin, however boundaries between compartments are rapidly broken after skin wounding.
- Wong VW*, Stange DE*, Page ME*, Buczacki S, Wabik A, Itami S, Van De Wetering M, Poulsom R, Wright NA, Trotter MW, Watt FM, Winton DJ, Clevers H & Jensen KB (2012). Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol, 14, 401-8. (*equal contribution)
- Page ME, Lombard P, Ng F, Gottgens B & Jensen KB (2013). The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell, 13, 471-82.
- Schepeler T, Page ME, Jensen KB (2014). Heterogeneity and plasticity of epidermal stem cells. Development, 141, 2559-2567. (Review article)