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Stem Cell Four-Year PhD Programme: Supervisors for 2019/20


Supervisor Research Field Location
Maria Alcolea

Epithelial Cell Fate and Plasticity; relevance for oesophageal cancer development

Jeffrey Cheah Biomedical Centre
Roger Barker

Clinical aspects of Parkinson's and Huntington's disease including the study of cell based therapies to treat patients and iPS/iN work to study disease pathogenesis and novel therapeutics

Brain Repair Centre
Srinjan Basu Single-cell and single-molecule imaging approaches in stem cell biology Jeffrey Cheah Biomedical Centre
Serena Best Medical materials Cambridge Centre for Medical Materials
Allan Bradley **

Leading the Sanger Institute's Mouse Genomics Team, which uses the mouse as a model system to investigate the function of individual genes

Wellcome Sanger Institute
Simon Buczacki

Colorectal cancers

Jeffrey Cheah Biomedical Centre
Ruth Cameron

Medical materials

Cambridge Centre for Medical Materials
Peter Campbell **

Cancer genomics

Wellcome Sanger Institute
Kevin Chalut

The physical biology of pluripotency and differentiation

Jeffrey Cheah Biomedical Centre
Ana Cvejic

Haematopoietic stem cells

Jeffrey Cheah Biomedical Centre
Sara-Jane Dunn **

Biological Computation

Microsoft Research
Robin Franklin

Factors regulating adult neural stem cell fate following CNS injury, with particular emphasis of oligodendrocyte differentiation

Jeffrey Cheah Biomedical Centre

Cédric Ghevaert

Production of platelet and red cells for transfusion in humans from pluripotent stem cells using reprogramming techniques

Jeffrey Cheah Biomedical Centre
Richard Gilbertson

Childhood brain tumours

Cambridge Cancer Centre

Bertie Göttgens *

The transcriptional control of normal and leukemic blood stem/progenitor cells

Jeffrey Cheah Biomedical Centre
Tony Green

Regulation and differentiation in normal haematopoietic stem cells and in myelo-proliferation disorders

Jeffrey Cheah Biomedical Centre
Brian Hendrich

Transcriptional control  of stem cell fates

Jeffrey Cheah Biomedical Centre
Daniel Hodson

Mutation timing in lymphomagenesis

Jeffrey Cheah Biomedical Centre

Meritxell Huch

Adult tissue regeneration and its implications in disease and cancer

Brian Huntly

Characterisation of the molecular and cellular biology of cancer stem cells and to compare and contrast these to normal stem cells

Jeffrey Cheah Biomedical Centre
Joo-Hyeon Lee

Stem cells and niches

Jeffrey Cheah Biomedical Centre
Phil Jones **

We use in vivo lineage tracing in transgenic mouse models to define normal stem and progenitor cell behaviour in squamous epithelia and how this is changed by mutations and carcinogens in preneoplasia

Wellcome Sanger Institute

Walid Khaled

Epithelial cell fate and tumour development

Department of Pharmacology

Ragnhildur Thóra Káradóttir

Neuronal activity and neurotransmitter regulation of central nervous systems stem/precursor cell fate

Jeffrey Cheah Biomedical Centre
David Kent

Single cell fate choice in normal and malignant stem cells

Jeffrey Cheah Biomedical Centre

András Lakatos

Developmental and pathological aspects of astrocyte-neuron interactions

Centre for Brain Repair 
Elisa Laurenti

Human haematopoietic stem cells in health and disease

Jeffrey Cheah Biomedical Centre

Alfonso Martinez Arias

The principles that govern cell fate transitions during development from the perspective of interactions between signalling and transcription factor networks

Dept of Genetics
Andrew McCaskie

Regenerative therapies for bone and cartilage repair

Jeffrey Cheah Biomedical Centre

Simón Méndez-Ferrer

Blood stem cell niches Jeffrey Cheah Biomedical Centre
Florian Merkle *

Human stem cell-based models of obesity and neurodegeneration

Jennifer Nichols

Embryonic pluripotency and its relationship to stem cells

Jeffrey Cheah Biomedical Centre
Anna Philpott

Proliferation versus differentiation in stem and progenitor cells

Jeffrey Cheah Biomedical Centre
Cristina Pina

Haematopoietic stem cells

Dept of Genetics
Wolf Reik ** Babraham Institute
Ingo Ringshausen

The dynamics, mechanisms and biological purposes of genome-wide epigenetic reprogramming in germ cells and early embryos

Jeffrey Cheah Biomedical Centre

Peter Rugg-Gunn **

Epigenetic mechanisms controlling pluripotency and differentiation in embryonic stem cells

Babraham Institute

José Silva

Biology of induced pluripotency

Jeffrey Cheah Biomedical Centre
Ben Simons

Mechanisms of stem cell fate in maintenance, repair and regeneration of adult tissues, and pathways leading to ageing and disease. Regulation of progenitor cell fate in late stage development of tissues

Cavendish Laboratory
Sanjay Sinha

Vascular diseases

Jeffrey Cheah Biomedical Centre
Austin Smith

Embryonic stem cells: self-renewal, pluripotency, commitment, lineage restriction, reprogramming

Jeffrey Cheah Biomedical Centre
Azim Surani *

Epigenetic regulation of cell fate determination from pluripotent stem cells

Ludovic Vallier

Mechanisms controlling differentiation in pluripotent stem cells into definitive endoderm

Jeffrey Cheah Biomedical Centre
George Vassiliou

Leukaemic haemopoietic stem cells

Jeffrey Cheah Biomedical Centre
Christine Watson

Stem and progenitor cell fate in mammary gland

Dept of Pathology
Doug Winton

Epithelial and cancer stem cells

Matthias Zilbauer

Intestinal stem cell biology

Dept. of Paediatrics

*  Supervisor is part of another Wellcome Four-Year Programme, so cannot take students from both Programmes in consecutive years. 

**  Non-University staff, therefore only eligible to co-supervise.

# Only eligible to co-supervise, due to primary commitment on another Wellcome 4-Year PhD Programme.


  • BRC - Brain Repair Centre
  • CIMR - Cambridge Institute for Medical Research
  • CR-UK, CRI - Cancer Research UK, Cambridge Research Institute
  • Gurdon - The Wellcome/Cancer Research UK Gurdon Institute
  • LRM - Anne McLaren Laboratory for Regenerative Medicine
  • LMB - MRC Laboratory of Molecular Biology
  • PDN - Department of Physiology, Development and Neuroscience