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Stem Cell Four-Year PhD Programme: Supervisors for 2017/18 (MRC Programme)


Supervisor Research Field Location
Maria Alcolea

Epithelial Cell Fate and Plasticity; relevance for oesophageal cancer development

SCI Gleeson Building
Roger Barker

Clinical aspects of Parkinson's and Huntington's disease including the study of cell based therapies to treat patients and iPS/iN work to study disease pathogenesis and novel therapeutics

Brain Repair Centre
Paul Bertone

Transcriptional regulation of pluripotency in ES cells and embryonic development

SCI Gleeson Building
Serena Best Medical materials Cambridge Centre for Medical Materials
Allan Bradley **

Leading the Sanger Institute's Mouse Genomics Team, which uses the mouse as a model system to investigate the function of individual genes

Wellcome Trust Sanger Institute
Simon Buczacki

Colorectal cancers

Cambridge Cancer Centre
Ruth Cameron

Medical materials

Cambridge Centre for Medical Materials
Peter Campbell **

Cancer genomics

Wellcome Trust Sanger Institute
Kevin Chalut

The physical biology of pluripotency and differentiation

SCI Gleeson Building
Anna Cvejic

Functional characterisation of novel genes implicated in human blood formation and pathologies using zebrafish as an in vivo model

Wellcome Trust Sanger Institute
Sara-Jane Dunn **

Biological Computation

Microsoft Research
Jasmin Fisher

Executable Biology; working to understand the orchestration of biological systems through construction, execution, and analysis of computational models

Department of Biochemistry

Robin Franklin

Factors regulating adult neural stem cell fate following CNS injury, with particular emphasis of oligodendrocyte differentiation

Clifford Albutt Building

Kristian Franze

CNS development and disease


Michaela Frye

Mechanism regulating stem cell self-renewal and differentiation processes in normal epithelial tissues and cancer

SCI Gleeson Building

Cédric Ghevaert

Production of platelet and red cells for transfusion in humans from pluripotent stem cells using reprogramming techniques

Richard Gilbertson

Childhood brain tumours

Cambridge Cancer Centre

Bertie Göttgens *

The transcriptional control of normal and leukemic blood stem/progenitor cells

Tony Green

Regulation and differentiation in normal haematopoietic stem cells and in myelo-proliferation disorders

Myriam Hemberger **

How stem cell self-renewal and differentiation is controlled

Babraham Institute
Brian Hendrich

Transcriptional control  of stem cell fates

SCI Gleeson Building
Daniel Hodson

Mutation timing in lymphomagenesis

Clifford Albutt Building

Meritxell Huch

Adult tissue regeneration and its implications in disease and cancer

Brian Huntly

Characterisation of the molecular and cellular biology of cancer stem cells and to compare and contrast these to normal stem cells

Joo-Hyeon Lee

Stem cells and niches

SCI Gleeson Building
Phil Jones **

We use in vivo lineage tracing in transgenic mouse models to define normal stem and progenitor cell behaviour in squamous epithelia and how this is changed by mutations and carcinogens in preneoplasia

Wellcome Trust Sanger Institute

Ragnhildur Thóra Káradóttir

Neuronal activity and neurotransmitter regulation of central nervous systems stem/precursor cell fate

SCI Gleeson Building
David Kent

Single cell fate choice in normal and malignant stem cells

Clifford Albutt Building

Elisa Laurenti

Human haematopoietic stem cells in health and disease

Clifford Albutt Building

Pentao Liu **

Stem cells in development and cancer, reprogramming and iPS cells

Wellcome Trust Sanger Institute
Rick Livesey *

Human stem cell models of neurological disease

Keith Martin

Stem cells as a potential treatment for glaucoma

Cambridge Neuroscience
Alfonso Martinez Arias

The principles that govern cell fate transitions during development from the perspective of interactions between signalling and transcription factor networks

Dept of Genetics
Andrew McCaskie

Regenerative therapies for bone and cartilage repair

Dept of Surgery, Addenbrooke's Hospital

Simón Méndez-Ferrer

Blood stem cell niches Cambridge Blood Centre, Dept. of Haematology
Florian Merkle *

Human stem cell-based models of obesity and neurodegeneration

Jennifer Nichols

Embryonic pluripotency and its relationship to stem cells

SCI Gleeson Building
Anna Philpott

Proliferation versus differentiation in stem and progenitor cells

Hutchison/MRC Research Centre, Dept. of Oncology
Cristina Pina

Haematopoietic stem cells

Stefano Pluchino

Mechanisms of stem cell-immune cell interactions and manipulation of stem cell functions towards repair and regeneration of the injured nervous system

Clifford Albutt Building

Wolf Reik **
Ingo Ringshausen

The dynamics, mechanisms and biological purposes of genome-wide epigenetic reprogramming in germ cells and early embryos

Clifford Albutt Building

David Rowitch

Glial cells and response to injury

Clifford Albutt Building

Peter Rugg-Gunn **

Epigenetic mechanisms controlling pluripotency and differentiation in embryonic stem cells

Babraham Institute

José Silva

Biology of induced pluripotency

SCI Gleeson Building
Ben Simons

Mechanisms of stem cell fate in maintenance, repair and regeneration of adult tissues, and pathways leading to ageing and disease. Regulation of progenitor cell fate in late stage development of tissues

Cavendish Laboratory
Sanjay Sinha

Vascular diseases

Dept. of Surgery, LRM
Austin Smith

Embryonic stem cells: self-renewal, pluripotency, commitment, lineage restriction, reprogramming

SCI Gleeson Building
Azim Surani *

Epigenetic regulation of cell fate determination from pluripotent stem cells

Ludovic Vallier

Mechanisms controlling differentiation in pluripotent stem cells into definitive endoderm

Dept. of Surgery, LRM
George Vassiliou

Leukaemic haemopoietic stem cells

Wellcome Trust Sanger Institute
Christine Watson

Stem and progenitor cell fate in mammary gland

Dept of Pathology
Doug Winton

Epithelial and cancer stem cells

Matthias Zilbauer

Intestinal stem cell biology

Dept. of Paediatrics, Addenbrooke's Hospital

*  Supervisor is part of another Wellcome Trust Four-Year Programme, so cannot take students from both Programme's in consecutive years.

**  Not eligible to be a primary supervisor, as they are not University staff. Can only be a Co-Supervisor.


  • BRC - Brain Repair Centre
  • CIMR - Cambridge Institute for Medical Research
  • CR-UK, CRI - Cancer Research UK, Cambridge Research Institute
  • Gurdon - The Wellcome Trust/Cancer Research UK Gurdon Institute
  • LRM - Anne McLaren Laboratory for Regenerative Medicine
  • LMB - MRC Laboratory of Molecular Biology
  • PDN - Department of Physiology, Development and Neuroscience