skip to content

Wellcome-MRC Cambridge Stem Cell Institute

 
Read more at: Wellcome to Professor Hiro Nakauchi

Wellcome to Professor Hiro Nakauchi

17 November 2016

Hiro Nakauchi obtained his M.D. from Yokohama City University School of Medicine and a Ph.D. in immunology from University of Tokyo Graduate School of Medicine. He isolated CD8 genes during his post-doc period at the Laboratory of Prof. Leonard Herzenberg, Stanford University. After coming back to Japan, he started working...


Read more at: New study illuminates ES Cells
New study illuminates ES Cells

New study illuminates ES Cells

17 November 2016

A collaboration between two EuropeanCommission projects, HEROIC and EuroSyStem, has cast new light on the study of embryonic stem (ES) cells. The research was led by HEROIC coordinator Professor Henk Stunnenberg, and EuroSyStem coordinator and SCI Director Professor Austin Smith. You can read the article here: Marks et al...


Read more at: Artificial liver cells win their creator prize for their potential to reduce animal experiments

Artificial liver cells win their creator prize for their potential to reduce animal experiments

17 November 2016

Cambridge research that created liver cells from stem cells has today been recognised with a national prize by the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs). Producing liver cells that demonstrate inherited liver diseases from human skin cells has earned Dr Ludovic Vallier...


Read more at: Under the Microscope

Under the Microscope

17 November 2016

Frye Lab researcher Claire Cox has provided the 10th video in the University of Cambridge Under the Microscope series. You can watch the video here . Under the Microscope is a collection of videos that show glimpses of the natural and man-made world in stunning close-up. They are released every Monday and Thursday via the...


Read more at: 4DCellFate Launch

4DCellFate Launch

17 November 2016

Barcelona, February 13th, 2012. As life begins, embryonic stem cells start to divide and develop into tissue ("differentiate"). Each stem cell has the potential to differentiate into different types of tissue cells, such as neurons, muscle, or blood cells, and the molecular mechanisms that determine its fate are highly...


Read more at: Brain Cells Created from Patient's Skin
Brain Cells Created from Patient's Skin

Brain Cells Created from Patient's Skin

17 November 2016

Cambridge scientists have, for the first time, created cerebral cortex cells – those that make up the brain’s grey matter – from a small sample of human skin. The researchers’ findings, which were funded by Alzheimer’s Research UK and the Wellcome Trust, were published today in Nature Neuroscience . Diseases of the...


Read more at: Smooth muscle cells created from patients’ skin cells
Smooth muscle cells created from patients’ skin cells

Smooth muscle cells created from patients’ skin cells

17 November 2016

Cambridge scientists have used skin stem cells to create vascular smooth muscle cells, which make up the walls of blood vessels. This research could pave the way to new treatments and better screening for cardiovascular disease. Read the full story on the University website.


Read more at: Breakthrough on MS Cure
Breakthrough on MS Cure

Breakthrough on MS Cure

17 November 2016

Stem Cell researchers at Cambridge and Edinburgh have discovered a promising stem cell therapy for multiple sclerosis. While much work is still needed to translate the discovery into an effective treatment, this breakthrough provides a promising road map towards a cure. A video story featuring the SCI's Robin Franklin can...


Read more at: Stem cell function and stress response are controlled by protein synthesis
Stem cell function and stress response are controlled by protein synthesis

Stem cell function and stress response are controlled by protein synthesis

16 November 2016

New article from the Frye Lab published in Nature Elevated protein synthesis and increased cell division rates are key physiological tasks for cancer cells and the protein translation machinery emerged as promising therapeutic target to control tumour growth. However, our study reveals that skin stem cells in both normal...


Read more at: Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient lacking NSUN3
Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient lacking NSUN3

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient lacking NSUN3

16 November 2016

New article from the Frye Lab in Nature Communications Mitochondrial disease is a chronic, genetic disorder caused by dysfunctional mitochondria, the organelles that generate energy for cells. Researchers used patient cells to identify a novel mechanism causing mitochondria to fail: Loss-of-function mutations in an enzyme...