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Bioinformatics

Core Bioinformatics Team

 

Head of Scientific Computing

Dr Irina Mohorianu,

 

Members:

Dr Susanne Bornelov, Research Associate - Bioinformatician,

Mrs Gabriele Adam, Research Assistant - Bioinformatician, gca27@cam.ac.uk

Mr Arash Shahsavari, Research Assistant - Bioinformatician

 

The CSCI Core Bioinformatics Group employs and creates computational approaches to gain insights into the biology of stem cells. The group performs both routine and customised data analyses for a wide range of genomics experiments in partnership with groups across the institute. This includes the use and development of computational pipelines for high-throughput sequencing applications, with particular expertise in coding and non-coding transcriptomics, epigenetics, single-cell profiling techniques and identification and characterisation of regulatory networks. Collaborative projects typically feature custom analytical solutions and close interaction with experimental labs.

Common elements of project execution include:

  • Design of high-throughput experiments in collaboration with SCI labs;
  • Liaison with platform providers to download experimental output;
  • Computational analysis of high-throughput assays, e.g. microarrays, sequencing data, and proteomics output;
  • Routine downstream analysis, data visualisation and interpretation of results;
  • Customised analyses driven by the particularities of an experiment/dataset
  • Customised database queries and information extraction;
  • Data storage and archiving, interaction with external data repositories;
  • Provision of methods, results and graphics for publication

The group also organises a series of training sessions in exploratory data analyses and statistical analyses for CSCI students and postdocs.

 

Contacts

For further information please direct enquiries to:   and bioinformatics@stemcells.cam.ac.uk.

 

Alumni:

Mr Michael Barber, Research Assistant - Bioinformatician (currently PhD student at U Edinburgh)