Core Bioinformatics Team

Head of Scientific Computing

Dr Irina Mohorianu, iim22@cam.ac.uk

Members:

Dr Susanne Bornelov, Research Associate - Bioinformatician, smb208@cam.ac.uk

Mrs Gabriele Adam, Research Assistant - Bioinformatician, gca27@cam.ac.uk

Mr Arash Shahsavari, Research Assistant - Bioinformatician

The CSCI Core Bioinformatics Group employs and creates computational approaches to gain insights into the biology of stem cells. The group performs both routine and customised data analyses for a wide range of genomics experiments in partnership with groups across the institute. This includes the use and development of computational pipelines for high-throughput sequencing applications, with particular expertise in coding and non-coding transcriptomics, epigenetics, single-cell profiling techniques and identification and characterisation of regulatory networks. Collaborative projects typically feature custom analytical solutions and close interaction with experimental labs.

Common elements of project execution include:

• Design of high-throughput experiments in collaboration with SCI labs;
• Liaison with platform providers to download experimental output;
• Computational analysis of high-throughput assays, e.g. microarrays, sequencing data, and proteomics output;
• Routine downstream analysis, data visualisation and interpretation of results;
• Customised analyses driven by the particularities of an experiment/dataset
• Customised database queries and information extraction;
• Data storage and archiving, interaction with external data repositories;
• Provision of methods, results and graphics for publication

The group also organises a series of training sessions in exploratory data analyses and statistical analyses for CSCI students and postdocs.

Contacts

For further information please direct enquiries to: iim22@cam.ac.uk  and bioinformatics@stemcells.cam.ac.uk.

Alumni:

Mr Michael Barber, Research Assistant - Bioinformatician (currently PhD student at U Edinburgh)