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Wellcome - MRC

Cambridge Stem Cell Institute

Studying at Cambridge



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Participating Supervisors on this Programme



Research Field

Location Theme
Maria Alcolea          

Epithelial Stem Cell fate and plasticity; relevance for oesophageal cancer development

SCI Gleeson Building
Roger Barker

Clinical aspects of Parkinson's and Huntington's disease including the study of cell based therapies to treat patients and iPS/iN work to study disease pathogenesis and novel therapeutics

BRC Neural
Paul Bertone

Transcriptional regulation of pluripotency in ES cells and embryonic development

SCI Gleeson Building
Allan Bradley

Leading the Sanger Institute's Mouse Genomics Team, which uses the mouse as a model system to investigate the function of individual genes

Wellcome Trust Sanger Institute
Kevin Chalut

The physical biology of pluripotency and differentiation

Cavendish Laboratory


Anna Cvejic

Functional characterisation of novel genes implicated in human blood formation and pathologies using zebrafish as an in vivo model

Wellcome Trust Sanger Institute


Robin Franklin

Factors regulating adult neural stem cell fate following CNS injury, with particular emphasis of oligodendrocyte differentiation

Clifford Albutt Building

Michaela Frye

Mechanism regulating stem cell self-renewal and differentiation processes in normal epithelial tissues and cancer

SCI Gleeson Building Epithelial Tissues

Cédric Ghevaert

Production of platelet and red cells for transfusion in humans from pluripotent stem cells using reprogramming techniques CIMR Haematopoiesis

Bertie Göttgens

The transcriptional control of normal and leukemic blood stem/progenitor cells

CIMR Haematopoiesis
Tony Green

Regulation and differentiation in normal haematopoietic stem cells and in myelo-proliferation disorders

CIMR Haematopoiesis
Myriam Hemberger

How stem cell self-renewal and differentiation is controlled

Babraham Institute
Brian Hendrich

Transcriptional control  of stem cell fates

SCI Gleeson Building


Meritxell Huch

Adult tissue regeneration and its implications in disease and cancer

Brian Huntly

Characterisation of the molecular and cellular biology of cancer stem cells and to compare and contrast these to normal stem cells

CIMR Haematopoiesis
Phil Jones

We use in vivo lineage tracing in transgenic mouse models to define normal stem and progenitor cell behaviour in squamous epithelia and how this is changed by mutations and carcinogens in preneoplasia

Wellcome Trust Sanger Institute Epithelial Tissues

Ragnhildur Thóra Káradóttir

Neuronal activity and neurotransmitter regulation of central nervous systems stem/precursor cell fate

SCI Gleeson Building Neural
David Kent

Single cell fate choice in normal and malignant stem cells

Clifford Albutt Building

Bon-Kyoung Koo Functional characterisation of E3 ubiquitin ligases in stem cell-niche interactions (Epithelial Tissues) SCI Gleeson Building Epithelial Tissues
Elisa Laurenti

Human haematopoietic stem cells in health and disease

Clifford Albutt Building

Pentao Liu

Stem cells in development and cancer, reprogramming and iPS cells

Wellcome Trust Sanger Institute
Rick Livesey

Human stem cell models of neurological disease

Gurdon Neural
Keith Martin

Stem cells as a potential treatment for glaucoma

Cambridge Neuroscience Neural
Alfonso Martinez Arias

The principles that govern cell fate transitions during development from the perspective of interactions between signalling and transcription factor networks

Dept of Genetics Pluripotency
Jennifer Nichols

Embryonic pluripotency and its relationship to stem cells

SCI Gleeson Building Pluripotency
Anna Philpott

Proliferation versus differentiation in stem and progenitor cells

Hutchison/MRC Research Centre, Dept. of Oncology Neural / Pancreas
Stefano Pluchino

Mechanisms of stem cell-immune cell interactions and manipulation of stem cell functions towards repair and regeneration of the injured nervous system

Clifford Albutt Building

Wolf Reik The dynamics, mechanisms and biological purposes of genome-wide epigenetic reprogramming in germ cells and early embryos Babraham Institute
Peter Rugg-Gunn

Epigenetic mechanisms controlling pluripotency and differentiation in embryonic stem cells

Babraham Institute

José Silva

Biology of induced pluripotency SCI Gleeson Building Pluripotency
Ben Simons Mechanisms of stem cell fate in maintenance, repair and regeneration of adult tissues, and pathways leading to ageing and disease. Regulation of progenitor cell fate in late stage development of tissues Cavendish Laboratory Pluripotency
Austin Smith Embryonic stem cells: self-renewal, pluripotency, commitment, lineage restriction, reprogramming SCI Gleeson Building Pluripotency
Azim Surani Epigenetic regulation of cell fate determination from pluripotent stem cells Gurdon Pluripotency
Ludovic Vallier Mechanisms controlling differentiation in pluripotent stem cells into definitive endoderm LRM Pluripotency
Christine Watson Stem and progenitor cell fate in mammary gland Dept of Pathology Epithelial Tissues
Doug Winton Epithelial and cancer stem cells




  • BRC - Brain Repair Centre
  • CIMR - Cambridge Institute for Medical Research
  • CR-UK, CRI - Cancer Research UK, Cambridge Research Institute
  • Gurdon - The Wellcome Trust/Cancer Research UK Gurdon Institute
  • LRM - Anne McLaren Laboratory for Regenerative Medicine
  • LMB - MRC Laboratory of Molecular Biology
  • PDN - Department of Physiology, Development and Neuroscience