News

Group Leader Dr Jyoti Nangalia has been awarded funding from the Rosetrees Trust for her project “Towards precision medicine: Integrating personalised prognostic predictions for patients with myeloid stem cell cancers into clinical care.”Dr Nangalia will be working with collaborators across Cambridge, including Co-Investigators Professor Brian Hunt…

Two Cambridge Stem Cell Institute Group Leaders are among the 63 scientists from around the world elected this year as Members and Associate Members of the European Molecular Biology Organisation (EMBO).EMBO Membership honours distinguished scientists who have made outstanding contributions to the life sciences, including 88 Nobel Laureates. It is …

Many congratulations to our institute and affiliate PIs who have been awarded promotions through the University’s Academic Promotions process recognising their outstanding work.Dr Cédric Ghevaert has been promoted to the position of Reader in Transfusion Medicine. Cédric is a group leader at the Stem Cell Institute and the Department of Haematology…

The expansion of ‘mutant’ cells that could lead to cancer is often kept in check by their neighbours, research from the Wellcome Sanger Institute, the University of Cambridge and their collaborators has found. The team discovered that when equally-matched cells in the oesophagus of mice coincided, they acted as a brake on one another’s growth.The s…

The Academy of Medical Sciences has elected 50 of the UK’s most prominent biomedical and health scientists to their Fellowship.The new Fellows have been chosen for their exceptional contributions to advancing biomedical science via world-leading research discoveries, running national science communication and engagement programmes and translating s…

Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells.The identification of these cells by researchers from the Wellcome Sanger Ins…

Research published in Nature Cell Biology today (Monday 30th March) has revealed insights into the molecular regulation of mammalian organ development.Shortly after fertilization, the mammalian embryo generates so called pluripotent cells, which have the capacity to contribute to all the future cell types of the organism. During a subsequent period…

New insights into the architecture of the brain have been revealed by scientists at the Wellcome Sanger Institute, the Wellcome-MRC Cambridge Stem Cell Institute and their collaborators. The researchers discovered that cells in the cerebral cortex of mice, called astrocytes, are more diverse than previously thought, with distinct layers of astrocyt…

Cancer of the immune system, called lymphoma or leukaemia, generally affects the entire body’s bone marrow and lymph nodes. Because these types of cancers are so widespread, surgery isn’t useful, so patients are usually treated with chemotherapy. Although these treatments have become significantly better in the past ten years, lymphoma and chronic …

Researchers at the Babraham Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), CRUK Cambridge Institute and the Wellcome – MRC Cambridge Stem Cell Institute have provided the first single-cell epigenomic analysis of gastrulation, a crucial process in early embryo development. The researchers analysed over 1,000 cells from mouse embryos…

The New York Stem Cell Foundation (NYSCF) announced the 2019 class of NYSCF – Robertson Investigators, welcoming six of the most talented stem cell researchers and neuroscientists into the NYSCF Investigator Program.The NYSCF Investigator Program fosters and encourages promising early career scientists whose cutting-edge research holds the potentia…

In a world first, scientists have created the human developmental liver cell atlas that provides crucial insights into how the blood and immune systems develop in the foetus. It maps changes in the cellular landscape of the developing liver between the first and second trimesters of pregnancy, including how stem cells from the liver seed other tiss…

New research published in Cell Stem Cell suggests a common diabetes drug could hold the key to stopping disease progression in multiple sclerosis (MS). The new finding offers hope to people living with advanced forms of the condition, who currently have no treatment and often see disability as inevitable.The MS Society funded research suggests alte…

Two new studies by an international team of researchers report progress in using stem cells to develop new therapies for Pelizaeus-Merzbacher disease (PMD), a rare genetic condition affecting boys that can be fatal before 10 years of age.Often diagnosed at birth with symptoms of weakness and breathing difficulties, the progressive neurological prob…

The healthy cells immediately surrounding a tumour become more stem cell-like and support cancer growth, reveals a new study published in Nature. The discovery was made during a research collaboration between Dr Joo-Hyeon Lee at the Wellcome – MRC Cambridge Stem Cell Institute and Dr Ilaria Malanchi at the Francis Crick Institute. The researchers…