Discovery Research Platform for Tissue Scale Biology

What is the Platform?

The Wellcome Discovery Research Platform for Tissue Scale Biology (DRP-TSB) will work over the next seven years to drive new waves of discovery and translational stem cell science across the molecular, cellular and tissue scales.

Based at the Cambridge Stem Cell Institute at the University of Cambridge, it aims to empower new ways of studying stem cell biology at the tissue and organ scale as well as create a network of researchers to capitalise on in vitro models for the development of better treatments for human patients.

The DRP-TSB will work with our interdisciplinary partners to combine six technology areas:

• Organ Culture
• Imaging
• Image Analysis
• Genomics
• Bioinformatics
• Tissue Modelling

Breaking down barriers

Within Cambridge, DRP connects researchers from a broad range of University departments, to facilitate the kind of interdisciplinary approaches that will be required to break down technology barriers to improve research at Tissue Scale.

Biomedical scientists perform research at multiple scales, ranging from molecules to entire human populations. While progress in some scales has been vast, there are still many questions to interrogate at tissue scale. This Platform will seek to dig into these questions, break down the barriers, and innovate through new experimental and computational methods with the goal of delivering new insights into the ways stem cells build, maintain and repair all our tissues and organs.

Key people

Bertie Gottgens  CSCI	Walid Khaled CSCI	Athina Markaki Dept of Engineering
Simon Mendez-Ferrer CSCI	Roisin Owens Dept of Chemical Engineering and Biotechnology	Sanjay Sinha CSCI

DRP Senior Researchers