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Clinical Trials

Institute researchers are involved in a number of active clinical trials which show promise for the translation of stem cell research from bench to bedside.

If you would like to find out more about clinical trials, please contact us on:

 

Trial Lead

Topic Description More details

Prof Roger Barker                                                             

Parkinson's disease

Effects of OXB-102 in patients with bilateral, idiopathic Parkinson's Disease. NCT03720418

Prof Roger Barker                                                                                

Parkinson's disease

TRANSEURO open label transplant study  in Parkinson's Disease. NCT01898390

Prof Robin Franklin                                                                                  

Multiple sclerosis

Retinoid X receptor gamma agonists in multiple sclerosis patients to regulate the differentiation of central nervous system progenitors into remyelinating oligodendrocytes. 2104-003145-99

Dr Cédric Ghevaert

Blood components

RESTORE - recovery and survival of stem cell originated red cells - currently pending approval from the Health Research Authority. RESTORE

Prof Brian Huntly

Haematologic malignancies

Dose escalation study to investigate the clinical activity of BET inhibitors in subjects with relapsed, refractory hematologic malignancies NCT01943851

Prof Andrew McCaskie

Osteoarthritis Evaluation the efficacy of adipose derived mesenchymal stromal cells in patients with knee osteoarthritis. NCT02838069

Dr Simón Méndez-Ferrer

Myeloproliferative neoplasms Redeployment of tamoxifen to modulate the bone marrow niche and treat myeloproliferative neoplasms 2015-05497-38

Prof David Rowitch

Connatal Pelizaeus-Merzbacher Disease Five-year long term follow-up study of a neural stem cell therapy trial for Connatal Pelizaeus-Merzbacher Disease NCT01005004 & NCT01391637