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Wellcome-MRC Cambridge Stem Cell Institute


Institute researchers are involved in a number of clinical trials that show promise for the translation of stem cell research from bench to bedside.

Below is a list of the current clinical trials underway from the researchers at CSCI. 


If you would like to find out more about clinical trials, please contact us at

Trial Lead

Topic Description More details

Prof Roger Barker

Parkinson's disease

A Trial to Determine the Safety and Tolerability of Transplanted Stem Cell Derived Dopamine Neurons to the Brains of Individuals With Parkinson's Disease (STEM-PD)


Prof Roger Barker

Parkinson's disease

TRANSEURO open label transplant study  in Parkinson's Disease. NCT01898390

Dr Cédric Ghevaert

Blood components

RESTORE - recovery and survival of stem cell originated red cells - currently pending approval from the Health Research Authority. RESTORE

Prof Andrew McCaskie

Osteoarthritis Evaluation the efficacy of adipose derived mesenchymal stromal cells in patients with knee osteoarthritis. NCT02838069

Dr Simón Méndez-Ferrer

Myeloproliferative neoplasms Redeployment of tamoxifen to modulate the bone marrow niche and treat myeloproliferative neoplasms 2015-05497-38
Dr Daniel Hodson High-grade B-cell Lymphoma DLBCL Interim Response Evaluation for Customised Therapy (DIRECT) NCT04226937
Professor Brian Huntly Chronic Myelogenous Leukemia Asciminib Treatment Optimization in ≥ 3rd Line CML-CP. NCT04948333
Prof Roger Barker Huntington’s disease A trial to look at how different doses of felodipine are tolerated in people with early-stage Huntington’s disease ISRCTN56240656
Dr Konstantinos Tzelepis Advanced Cancer Oral Administration of STC-15 in Subjects With Advanced Malignancies NCT05584111