Cancer cells ‘corrupt’ their healthy neighbours

The healthy cells immediately surrounding a tumour become more stem cell-like and support cancer growth, reveals a new study published in Nature. The discovery was made during a research collaboration between Dr Joo-Hyeon Lee at the Wellcome – MRC Cambridge Stem Cell Institute and Dr Ilaria Malanchi at the Francis Crick Institute.

Discovering the numerous paths of stem cell decision making

How cells change their identity to become a different cell type and the route they follow to reach their final form is a fundamental unanswered question at the heart of developmental biology.

Cambridge scientists reverse ageing process in rat brain stem cells

New research, published today in Nature, reveals how increasing brain stiffness as we age causes brain stem cell dysfunction, and demonstrates new ways to reverse older stem cells to a younger, healthier state.