Research at the Cambridge Stem Cell Institute falls under three key themes: Stem Cell States, Stem Cells in Disease, Stem Cells & Therapeutics. Many of our scientists contribute to more than one theme, and within these themes we have particular strengths in pluripotency, haematopoiesis, neural and epithelial stem cells.
Theme 1: Stem Cell States
Establishing new understanding of stem cell biology and behaviour complements and informs our studies of stem cell dysfunction in disease and provides the foundation of our translational aspirations for stem cells and therapeutics.
Theme 2: Stem Cells in Disease
Many disease states arise (malignancies) or persist (regeneration failure) as a result of stem and progenitor cell dysfunction. Underpinned by our exploration of normal stem cell states, we are investigating the mechanisms responsible for pathological behaviours of stem and progenitor cells.
Theme 3: Stem Cells & Therapeutics
Building on the research undertaken into stem cell states and stem cells in disease, Institute researchers are using stem cells to model diseases in vitro and to generate new diagnostic and therapeutic approaches to deliver patient benefit.