Building on the research undertaken into stem cell states and stem cells in disease, Institute researchers are using stem cells to model diseases in vitro and to generate new diagnostic and therapeutic approaches to deliver patient benefit.
Several investigators are developing first-in-human clinical trials of cellular therapies using stem cell derivatives, while others work on new diagnostic and prognostic approaches to improve patient outcomes.
The Institute has a range of group leaders working across different topics within the stem cells & therapeutics theme, details listed below. More information on each researcher's specific area can be found on their group pages.
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Parkinson's and Huntington's disease Key diseases: Parkinson's disease & Huntington's disease |
In vitro production of platelets for transfusion |
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Establishing how blood stem cells are subverted in blood cancers. Key disease: Myeloproliferative neoplasms |
Leukaemia stem cell biology and leukaemogenesis Key diseases: Leukaemia and Lymphoma |
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Regenerative therapies for bone and cartilage repair Key disease: Arthritis |
Blood stem cell niches Key disease: Myeloproliferative neoplasms |
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Investigating how genes determine development and diversity of glial cells in the brain. Key disease: Connatal Pelizaeus-Merzbacher Disease |
Vascular diseases Key disease: Cardiovascular disease |
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Leukaemic haemopoietic stem cells Key disease: Leukaemia |
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