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Wellcome-MRC Cambridge Stem Cell Institute


Building on the research undertaken into stem cell states and stem cells in disease, Institute researchers are using stem cells to model diseases in vitro and to generate new diagnostic and therapeutic approaches to deliver patient benefit.

Several investigators are developing first-in-human clinical trials of cellular therapies using stem cell derivatives, while others work on new diagnostic and prognostic approaches to improve patient outcomes.

The Institute has a range of group leaders working across different topics within the stem cells & therapeutics theme, details listed below. More information on each researcher's specific area can be found on their group pages.


Roger Barker 2020

Prof Roger Barker

Parkinson's and Huntington's disease


Key diseases: Parkinson's disease & Huntington's disease     

128-Franklin 2017

Prof Robin Franklin

Studying neural stem cells and central nervous system regeneration.


Key disease: Multiple sclerosis


Dr Cédric Ghevaert

In vitro production of platelets for transfusion


Prof Tony Green

Establishing how blood stem cells are subverted in blood cancers.


Key disease: Myeloproliferative neoplasms


Prof Brian Huntly

Leukaemia stem cell biology and leukaemogenesis


Key diseases: Leukaemia and Lymphoma

107-McCaskie 2017

Prof Andrew McCaskie

Regenerative therapies for bone and cartilage repair


Key disease: Arthritis


Dr Simón Méndez-Ferrer

Blood stem cell niches


Key disease: Myeloproliferative neoplasms


Prof David Rowitch

Investigating how genes determine development and diversity of glial cells in the brain.

Key diseaseConnatal Pelizaeus-Merzbacher Disease


Dr Sanjay Sinha

Vascular diseases


Key disease: Cardiovascular disease


Prof Ludovic Vallier

Researching how stem cells become adult tissues, including liver pancreas and lung.


Professor George Vassiliou

Leukaemic haemopoietic stem cells


Key disease: Leukaemia