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Wellcome-MRC Cambridge Stem Cell Institute

dopaminergic neurons differentiated from human pluripotent stem cells

Building on the research undertaken into stem cell states and stem cells in disease, Institute researchers are using stem cells to model diseases in vitro and to generate new diagnostic and therapeutic approaches to deliver patient benefit.

Several investigators are developing first-in-human clinical trials of cellular therapies using stem cell derivatives, while others work on new diagnostic and prognostic approaches to improve patient outcomes.

The Institute has a range of group leaders working across different topics within the stem cells & therapeutics theme, details listed below. More information on each researcher's specific area can be found on their group pages.


Prof Roger Barker

Parkinson's and Huntington's disease

Key diseases: Parkinson's disease & Huntington's disease     



Dr Cédric Ghevaert

In vitro production of platelets for transfusion


Prof Tony Green

Establishing how blood stem cells are subverted in blood cancers.

Key disease: Myeloproliferative neoplasms



Prof Brian Huntly

Leukaemia stem cell biology and leukaemogenesis

Key diseases: Leukaemia and Lymphoma


Prof Andrew McCaskie

Regenerative therapies for bone and cartilage repair

Key disease: Arthritis



Dr Simón Méndez-Ferrer

Blood stem cell niches

Key disease: Myeloproliferative neoplasms


Prof David Rowitch

Investigating how genes determine development and diversity of glial cells in the brain.

Key diseaseConnatal Pelizaeus-Merzbacher Disease



Dr Sanjay Sinha

Vascular diseases

Key disease: Cardiovascular disease


Professor George Vassiliou

Leukaemic haemopoietic stem cells

Key disease: Leukaemia