Building on the research undertaken into stem cell states and stem cells in disease, Institute researchers are using stem cells to model diseases in vitro and to generate new diagnostic and therapeutic approaches to deliver patient benefit.
Several investigators are developing first-in-human clinical trials of cellular therapies using stem cell derivatives, while others work on new diagnostic and prognostic approaches to improve patient outcomes.
The Institute has a range of group leaders working across different topics within the stem cells & therapeutics theme, details listed below. More information on each researcher's specific area can be found on their group pages.
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Parkinson's and Huntington's disease
Key diseases: Parkinson's disease & Huntington's disease |
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Studying neural stem cells and central nervous system regeneration.
Key disease: Multiple sclerosis |
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In vitro production of platelets for transfusion |
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Establishing how blood stem cells are subverted in blood cancers.
Key disease: Myeloproliferative neoplasms |
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Leukaemia stem cell biology and leukaemogenesis
Key diseases: Leukaemia and Lymphoma |
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Regenerative therapies for bone and cartilage repair
Key disease: Arthritis |
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Blood stem cell niches
Key disease: Myeloproliferative neoplasms |
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Investigating how genes determine development and diversity of glial cells in the brain. Key disease: Connatal Pelizaeus-Merzbacher Disease |
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Vascular diseases
Key disease: Cardiovascular disease |
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Researching how stem cells become adult tissues, including liver pancreas and lung. |
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Leukaemic haemopoietic stem cells
Key disease: Leukaemia |
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