Dr Kristian Franze
Dr Kristian Franze
CNS development and disease
Departmental Affiliation: Department of Physiology, Development and Neuroscience
Research
Mechanobiology of nervous system development and pathology. We are taking an interdisciplinary approach to investigate how cellular forces, local cell and tissue compliance and cellular mechanosensitivity contribute to CNS development and disease. Methods we are exploiting include atomic force microscopy, traction force microscopy, custom-built soft cell culture substrates, substrate patterning, and cell and molecular biological techniques. We are mostly interested in the early development of the African clawed frog Xenopus laevis.