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Wellcome-MRC Cambridge Stem Cell Institute


It is increasingly clear that stem cell dysfunction underlies many of the health challenges facing the world today. From neurodegenerative and cardiovascular diseases to cancer and ageing, stem cell dysregulation is implicated across the disease spectrum.

Our researchers are working across the disease spectrums to harness the therapeutic potential of stem cells.

Arthritis Arthritis is a common condition that causes pain and inflammation in a joint. In the UK, more than 10 million people have arthritis or other similar conditions that affect the joints. Arthritis affects people of all ages, including children. More information here. Prof Andrew McCaskie
Cardiovascular disease Cardiovascular disease is a general term for conditions affecting the heart of blood vessels. Cardiovascular disease is one of the main causes of death and disability in the UK but it can often largely be prevented by leading a health lifestyle. More information here. Dr Sanjay Sinha
Huntington's disease

Huntington's disease is a condition that stops parts of the brain working properly over time. It's passed on (inherited) from a person's parents. It gets gradually worse over time and is usually fatal after a period of up to 20 years. More information here.

Prof Roger Barker

Leukaemia is a type of blood cancer that affects blood cells - usually white blood cells. There are a number of different types of leukaemia. More information here.

Prof Bertie Göttgens, Prof Brian Huntly, Dr Elisa Laurenti, Dr Ingo Ringshausen & Prof George Vassiliou                    

Lymphoma is cancer that affects a type of white blood cell called lymphocytes which are found in your blood, bone marrow and lymph glands. There are different types of lymphoma. More information here.

Dr Daniel Hodson, Prof Brian Huntly & Dr Ingo Ringshausen
Multiple Sclerosis

Multiple sclerosis (MS) is a condition that can affect the brain and spinal cord, causing a wide range of potential symptoms, including problems with vision, arm or leg movement, sensation or balance. It's a lifelong condition that can sometimes cause serious disability. MS is one of the most common causes of disability in younger adults. More information here.

Dr Ragnhildur Thóra Káradóttir

Myeloproliferative Neoplasms

Myeloproliferative Neoplasms are a group of rare disorders of the bone marrow that cause an increase in the number of blood cells. More information here.

Prof Tony Green

Parkinson's disease Parkinson's disease is a condition in which part of the brain become progressively damaged over many years. The three main symptoms are: involuntary shaking of particular parts of the body, slow movement and stiff and inflexible muscles. Parkinson's disease is caused by a loss of nerve cells in a part of the brain called the substantia nigra. This leads to a reduction in a chemical called dopamine in the brain, which plays a vital role in regulating the movement of the body. More information here. Prof Roger Barker                                                                                                                                                                                                                                                          
Pelizaeus-Merzbacher disease Pelizaeus-Merzbacher disease (PMD) is a rare, progressive, degenerative central nervous system disorder in which coordination, motor abilities, and intellectual function deteriorate. The disease is caused by a mutation in the gene that controls the production of a myelin protein. PMD is inherited as an X-linked recessive trait. More information here. Prof David Rowitch