News

Stem cell function and stress response are controlled by protein synthesis

16 November 2016

New article from the Frye Lab published in Nature Elevated protein synthesis and increased cell division rates are key physiological tasks for cancer cells and the protein translation machinery emerged as promising therapeutic target to control tumour growth. However, our study reveals that skin stem cells in both normal...

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient lacking NSUN3

16 November 2016

New article from the Frye Lab in Nature Communications Mitochondrial disease is a chronic, genetic disorder caused by dysfunctional mitochondria, the organelles that generate energy for cells. Researchers used patient cells to identify a novel mechanism causing mitochondria to fail: Loss-of-function mutations in an enzyme...

Anatomy of a decision: mapping early development

16 November 2016

A new atlas of gene expression during the earliest stages of life boosts studies of development - new study published in Nature led by CSCI researchers from the Gottgens Lab and the European Bioinformatics Institute (EMBL-EBI). In the first genome-scale experiment of its kind, researchers have gained new insights into how...

Scientists identify ‘cell of origin’ in skin cancers

16 November 2016

Scientists have identified for the first time the ‘cell of origin’ – in other words, the first cell from which the cancer grows – in basal cell carcinoma, the most common form of skin cancer, and followed the chain of events that lead to the growth of these invasive tumours. Until now, there has been intense interest in...

Sall4 controls differentiation of pluripotent cells independently of the NuRD complex

16 November 2016

Scientists have identified the function of Sall4, a protein important in early development and a hallmark of many cancers. In their paper, published in Development, they show that Sall4 functions to control gene expression in early embryonic cells, controlling their entry into the neural lineage. It is proposed that Sall4...

Breast cancer scientists use innovative 3D imaging to help track cancer cells

16 November 2016

New article from SCI Affiliate Christine Watson's Lab published in Nature Communications describes a ground-breaking project which tracked the fate of ‘daughter cells’ to find out how cancer moves around the breast from a single stem cell. The cells of the breast undergo a massive expansion during puberty and with every...

Interview with Rick Livesey

16 November 2016

Interview with Rick Livesey about his stem cell 'mini brains' that can help researchers study the progression of Alzheimer's disease in the Sunday Express.

Athena SWAN Bronze Award

16 November 2016

The Cambridge Stem Cell Institute is proud to announce that we have received an Athena SWAN Bronze Award for our commitment to equality. The awards recognise commitment to advancing women’s careers in science, technology, engineering, maths and medicine in higher education and research. Learn more about Athena SWAN here.

Prof Roger Barker elected to the Fellowship of the Academy of Medical Sciences

16 November 2016

This year, SCI PI, Professor Roger Barker was one of the five Cambridge researchers awarded. The Academy of Medical Sciences promotes advances in medical science and campaigns to ensure these are translated into benefits for patients. The Academy’s Fellows are the United Kingdom’s leading medical scientists from hospitals...

Ragnhildur Thóra Káradóttir receives Lister Research Prize

16 November 2016

SCI Group Leader Dr Ragnhildur Thóra Káradóttir has received a Lister Research Prize for her work on the role of neuronal activity in myelin repair. The Lister Institute Research Prize Fellowships are one-off awards which seek to help support and nurture future leaders of biomedical research. The Fellowships offer a...

Stem cell function and stress response are controlled by protein synthesis

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient lacking NSUN3

Anatomy of a decision: mapping early development

Scientists identify ‘cell of origin’ in skin cancers

Sall4 controls differentiation of pluripotent cells independently of the NuRD complex

Breast cancer scientists use innovative 3D imaging to help track cancer cells

Interview with Rick Livesey

Athena SWAN Bronze Award

Prof Roger Barker elected to the Fellowship of the Academy of Medical Sciences

Ragnhildur Thóra Káradóttir receives Lister Research Prize

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