Biography
Dr. Andrian Yang is a Senior Computational Scientist in the Discovery Research Platform for Tissue Scale Biology, part of the Cambridge Stem Cell Institute. Prior to his current position, he did his postdoctoral research in EMBL-EBI and IMS Metabolic Research Laboratories with John Marioni and Florian Merkle on single-cell characterisation of human induced pluripotent cells (hiPSC)-derived POMC neurons. His research interest includes single cell and bulk omics analysis, computational method development and biological data visualisation.
Publications
Chen, H.-J. C.*, Yang, A.*, Mazzaferro, S., Mali, I., Cahn, O., Kentistou, K., Rowley, C.,
Stewart, N., Seah, J. W. E., Pisupati, V., Kirwan, P., Aggarwal, S., Toyohara, T., Florido, M. H. C., Cowan, C. A., Quambusch, L., Hyvönen, M., Livesey, M. R., Perry, J. R. B., ... Merkle, F. T. (2023). Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss. In bioRxiv. https://doi.org/10.1101/2023.07.18.549357
Pantazis, C. B.*, Yang, A.*, Lara, E.*, McDonough, J. A.*, Blauwendraat, C.*, Peng, L.*, Oguro, H., Kanaujiya, J., Zou, J., Sebesta, D., Pratt, G., Cross, E., Blockwick, J., Buxton, P., Kinner-Bibeau, L., Medura, C., Tompkins, C., Hughes, S., Santiana, M., ... Merkle, F. T. (2022). A reference human induced pluripotent stem cell line for large- scale collaborative studies. Cell Stem Cell, 29(12), 1685-1702.e22. https://doi.org/10.1016/j.stem.2022.11.004
Berrens, R. V., Yang, A., Laumer, C. E., Lun, A. T. L., Bieberich, F., Law, C.-T., Lan, G., Imaz, M., Bowness, J. S., Brockdorff, N., Gaffney, D. J., & Marioni, J. C. (2022). Locus-specific expression of transposable elements in single cells with CELLO-seq. Nature Biotechnology, 40(4), 546–554. https://doi.org/10.1038/s41587-021-01093-1
Yang, A.*, Tang, J. Y. S.*, Troup, M., & Ho, J. W. K. (2022). Scavenger: A pipeline for recovery of unaligned reads utilising similarity with aligned reads. F1000Research, 8, 1587. https://doi.org/10.12688/f1000research.19426.2
Yang, A., Kishore, A., Phipps, B., & Ho, J. W. K. (2019). Cloud accelerated alignment and assembly of full-length single-cell RNA-seq data using Falco. BMC Genomics, 20(S10). https://doi.org/10.1186/s12864-019-6341-6
