News

CSCI scientists engage the public at European Researchers Night!

8 October 2018

On Friday (28 th ) and Saturday (29 th ) of September, Researchers from the Cambridge Stem Cell Institute took part in the largest public science event in Europe, European Researchers Night. Led by the Wellcome Genome Campus, LifeLab aims to bring cutting edge research to communities with limited access to science through...

New research reveals earliest step of lymphoid differentiation

5 October 2018

Blood stem cells produce all blood cell types throughout life, including red blood cells that transport oxygen throughout our body and white blood cells called lymphocytes that help us fight infections. New research using cutting-edge single cell technologies reveals that the regulation of the balance between red and white...

Family tree of blood production reveals hundreds of thousands of stem cells

5 September 2018

Adult humans have many more blood-creating stem cells in their bone marrow than previously thought, ranging between 50,000 and 200,000 stem cells. Researchers from the Wellcome Sanger Institute and Wellcome – MRC Cambridge Stem Cell Institute developed a new approach for studying stem cells, based on methods used in...

Potential target for lung cancer treatment discovered

29 August 2018

Scientists have identified a key molecular player in a subtype of lung cancer which could lead to a new way to tackle the disease, according to research published in Nature Communications . Cambridge based scientists and their collaborators found lung squamous cell carcinoma (LUSC) cells contained high amounts of a protein...

Roots of Leukaemia reveal possibility of predicting people at risk

9 July 2018

Scientists have discovered that it is possible to identify people at high risk of developing acute myeloid leukaemia (AML) years before diagnosis. The researchers from the Cambridge Stem Cell Institute, Wellcome Sanger Institute, European Bioinformatics Institute (EMBL-EBI) and their international collaborators found that...

Scientists reveal new insights into the role of the NuRD Complex in gene expression

28 June 2018

Work published today by the Hendrich lab solves a major conundrum in the chromatin field: how can a single chromatin remodelling complex activate expression at some genes while repressing expression at others? While the vast majority of cells in the body contain exactly the same set of genetic instructions, they...

International Stem Cell Art Exhibition Comes to Cambridge

15 June 2018

“If stem cells were the artistic medium by which we design our future, what does the future look like?” Stem cells have the extraordinary ability to develop into any type of cell in the body. They also have huge potential for use in the treatment of diseases and in regenerative medicine. To explore the future of stem cell...

New stem cell research fundamentally changes our understanding of male and female early development

24 May 2018

Cambridge stem cell scientists have revealed new insight into sex chromosome changes in embryos that fundamentally alters the way we think about male and female early development. In research published in the journal Cell Stem Cell , the scientists showed for the first time that a process called ‘X Chromosome Inactivation...

Cambridge Stem Cell Scientists elected as EMBO Members

17 May 2018

Three Cambridge Stem Cell Scientists, Prof Ben Simons , Dr Michaela Frye and Dr Peter Campbell , have this week been elected as members of the European Molecular Biology Organisation (EMBO), joining a group of more than 1800 of the best researchers in Europe and around the world. “EMBO Members are leading scientists...

Leukaemia protective role of Y chromosome gene discovered

4 May 2018

Scientists have discovered the first leukaemia protective gene that is specific to the male-only Y chromosome. Researchers at the Wellcome Sanger Institute and the Wellcome - MRC Cambridge Stem Cell Institute found that this Y-chromosome gene protects against the development of Acute Myeloid Leukaemia (AML) and other...