News

Researchers discover how leukaemia-associated gene mutations steadily commandeer blood cell production over a lifetime, and how these changes relate to ageing and cancer development.New research has uncovered how genetic mutations hijack the production of blood cells in different periods of life. Scientists at the Wellcome-MRC Cambridge Stem Cell I…

Researchers have discovered how genetic mutations accumulated slowly over a lifetime lead to dramatic changes in blood formation after 70, providing a new theory for ageingNew research has uncovered how genetic changes that accumulate slowly in blood stem cells throughout life are likely to be responsible for the dramatic change in blood production…

Dr Richard Tyser will join Cambridge Stem Cell Institute as a Principal Investigator this summer, bringing his expertise on the emergence of form and function during early heart development. Dr Tyser is coming from his post at the University of Oxford in the Department of Physiology, Anatomy and Genetics, where in 2018 he received a British Heart F…

A new study was published today (10 March) in Cell Stem Cell, answering a question that’s been sitting unanswered for over thirty years. The research, led by Professor Simón Méndez-Ferrer’s Lab at Wellcome-MRC Cambridge Stem Cell Institute (CSCI), finally identified Interleukin-6 as a driver of an important switch that links the nervous system and …

Research finds identifiers that can speed the process of in-vitro platelet productionA new paper from the Wellcome-MRC Cambridge Stem Cell Institute (CSCI) and the UK Regenerative Medicine Platform has identified previously unknown markers of cells called megakaryocyte progenitors. This discovery will lead to better understanding of these important…

New research from the Wellcome-MRC Cambridge Stem Cell Institute (CSCI) and the Department of Physiology, Development, and Neuroscience at the University of Cambridge (PDN) explores the self-organisation of tissues in early embryos, offering an explanation for how cells sort themselves as they develop.The paper, published 22 February in Cell, disco…

Dr Konstantinos Tzelepis will join Cambridge Stem Cell Institute as a Principal Investigator, with research focusing on RNA modifications in stem cell homeostasis. ​​Dr Tzelepis will be moving from The Milner Therapeutics Institute, where he also served as a PI. Prior to his appointment at Milner, he was a Wellcome Trust Sir Henry Wellcome Fellow a…

Researchers have identified a new therapeutic target that could be critical in developing improved treatments for thrombocythaemiaA new study from the Wellcome-MRC Cambridge Stem Cell Institute (CSCI), the Wellcome Sanger Institute, Department of Haematology at the University of Cambridge and Cambridge Institute for Medical Research (CIMR) investig…

Unlocking the secrets of human milk cellsA new study from the Wellcome-MRC Cambridge Stem Cell Institute (CSCI) and the Department of Pharmacology at the University of Cambridge explores the cellular changes that occur in human mammary tissue in lactating and non-lactating women, offering insight into the relationship between pregnancy, lactation, …

Genetic mutations causing a type of adult blood cancer occur in childhood or even in the womb, new research has shown.A new study from the Wellcome Sanger Institute and the University of Cambridge has traced these mutations to childhood, showing that they proliferate in the body over decades before cancer symptoms later in life.The paper, published…

Over the winter holidays, Professor Robin Franklin of Cambridge Stem Cell Institute (CSCI) travelled to Saudi capital Riyadh to accept the King Faisal Prize for Medicine for his work in regenerative medicine for neurological conditions. He is a co-laureate for the prize alongside Professor Stephen Strittmatter from Yale University. This prestigious…

Last week it was announced that Professor Bertie Göttgens has been appointed as Director of Wellcome-MRC Cambridge Stem Cell Institute (CSCI) in January 2022. “In addition to his outstanding science, spanning several disciplines and tissues, Bertie has been a pillar of strength for the Institute,” wrote Professor Tony Green, current Director of CSC…

Our postgraduate students launched the Institute's first major hybrid meeting – our Annual PhD Symposium 2021.This entirely student-led event was a very significant one for our Postgraduates as last year's 2020 meeting was cancelled due to the global pandemic. In 2020, not only were the students unable to attend their yearly meet-up, but some were …

Nicole Mende's submission received first place prize in the ISEH New Investigator Awards (Postdoctoral Fellow category 2021).Mende is a Post-doc researcher based here at the Wellcome-MRC Cambridge Stem Cell Institute, in Principal Investigator Elisa Laurenti's Lab. She has received the New Investigator Award Winner for her top scoring abstract – 'I…

A total of 23 new Postgraduate students started here in the CSCI on Monday 4, October 2021, under the supervision of 12 different PIs within the Institute.These students are on a variety of PhD and Masters programmes and have now completed a full week of induction sessions. It was fantastic to see the majority of them in person around the building …